Syntheses of protoporphyrin-IX derivatives bearing extended propionate side-chains.

نویسندگان

  • Robert T Holmes
  • Jianming Lu
  • Celinah Mwakwari
  • Kevin M Smith
چکیده

In order to investigate the relationship between depth within membranes of singlet oxygen generation and effectiveness of photodynamic therapy of tumors, analogs of protoporphyrin-IX 1 bearing five 4 and seven 5 carbon atoms (in place of the 3-carbon atom chain in 1) were synthesized from monopyrrole precursors.

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عنوان ژورنال:
  • ARKIVOC : free online journal of organic chemistry

دوره 2010 5  شماره 

صفحات  -

تاریخ انتشار 2009